Hunter Syndrome is a rare X-linked disease that is named after physician Charles A. Hunter. This disease is also known as Mucopolysaccharidosis. This disease falls under a lysosomal storage disorder. This disease was described in 1917 but most discovers were made in the 1940s to more resent.
The protein that is produced by iduronate-2-sulfatase is glycosaminoglycans or (GAG)
Hunter Syndrome is a recessive trait that is inherited from the mother. There is a 25% of the child to have or carry Hunter syndrome when the mother has the gene. Hunter syndrome is mostly in males but there has been a few cases that a female has had Hunter syndrome. Hunter syndrome has been found in all ethnic groups. It is inherited on the X-link.
Sadly for the kids that are diagnosed with Hunter syndrome they will likely die in their second decade of their life.
There is current research enzyme replacement therapy and many are being to study stem cell transplants.
Work cited
"Hunter Syndrome." Check Orphan, www.checkorphan.org/diseases/hunter-syndrome. Accessed 4 Feb. 1017.
Polgreen, Lynda E., et al. "Pilot study of the safety and effect od abalimumab on pain, physical function, and musculoskeletal diseass in mucopolysaccharidosis types l and ll." PubMed Central, www.ncbi.nlm.nih.gov/pmc/articles/PMC5238608/. Accessed 3 Feb. 2017.
Wraith, J. Edmond, et al. "Initial repost from the Hunter Outcome Survey."Genetics in Medicine, www.nature.com/gim/journal/v10/n7/full/gim200879a.html. Accessed 2 Feb. 2017.
Pictures
https://www.youtube.com/watch?v=EryatDgmjog
http://www.mayoclinic.org/diseases-conditions/hunter-syndrome/symptoms-causes/dxc-20165662
http://hunterssyndrome.weebly.com/mucopolysaccharidosis.html
http://armagen.com/our-focus/hunter-syndrome/