Craniosynostosis LQB382 Developmental Anatomy & Tissue Adaptation
Craniosynostosis is a condition where one or more cranial sutures close prematurely altering the growth of the skull. This results in an abnormal skull shape. This can have significant effects on the growth of the brain and limit moulding of the skull during parturition.
Sagittal craniosynostosis
Most common form of craniosynostosis (~50%). Restricts transverse growth resulting in elongation of skull anteriorly and posteriorly.
Metopic craniosynostosis
20-25% of all cases of craniosynostosis. Results in a triangular forehead (narrow and pointed) with close-set orbital cavities.
Unilateral coronal craniosynostosis
~15% of craniosynostosis cases. Results in asymmetric growth of the skull resulting in a widening and increased height of the skull with a shorter length anterior to posterior. Bilateral coronal craniosynostosis is less frequent.
