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March/April 2022 - Adolescent Medicine Trials Network for HIV/AIDS Interventions

ATN - Adolescent Medicine Trials Network for HIV/AIDS Interventions. ATN Website: atnweb.org/atnweb

Follow us on Twitter at @atn_web

Sent from the Collaborative Studies Coordinating Center, Department of Biostatistics at the University of North Carolina's Gillings School of Global Public Health.

TO UNSUBSCRIBE: Email ccritz@email.unc.edu

For COVID-19-related updates on ATN funding, activities, and publications, click here.

The 2022 Spring ATN Virtual Meeting

Agenda Now Available

The agenda for the full meeting is available now - click here to view. The meeting will be held April 27-28, 2022 virtually. If you need assistance registering, email atnhelp@unc.edu.

What Did TERA Tell Us?

ATN 152, the TERA study, involved video-call coaching sessions and real-time, escalating medication adherence support by text and phone call for youth living with HIV. Participants also used a electronic dose monitoring device. How did these activities impact adherence to the youth participants' viral suppression of HIV?

Lessons learned, what participants said about the study, and more information from the TERA team can be seen on this newly launched series of webpages on the ATN website.

Hear from people directly involved in the TERA study in this video.

Cabenuva for HIV Treatment Approved by US FDA for Virologically Suppressed Adolescents

HIV treatment in the form of Cabenuva was recently approved by the US Food and Drug Administration for youth age 12 and over (who weigh at least 35kg, among other requirements). Interim data from an International Maternal Pediatric Adolescent AIDS Clinical Trials Network (IMPAACT) study, MOCHA, informed the FDA's decision - see more on IMPAACT's website.

Also see from December 2021 - Long-Acting, Injectable PrEP Option Approved: US Food and Drug Administration Includes Adolescents in Approval.

Publications

Rates of Sexually Transmitted Infection Diagnosis Among US Youth with Perinatally and Nonperinatally Acquired HIV. Published in the journal Sexually Transmitted Diseases.

PrEParing for NextGen: Cognitive Interviews to Improve Next Generation PrEP Modality Descriptions for Young Men Who have Sex with Men. Published in the journal AIDS and Behavior.

Implementation of Evidence-Based Practices to Reduce Youth HIV Transmission and Improve Self-Management: A Survey of Key Stakeholder Perspectives. Published in the journal AIDS Patient Care and STDS.

Using Machine Learning to Predict Young People’s Internet Health and Social Service Information Seeking. Published in the journal Prevention Science.

PrEParing for long-acting injectable PrEP in the South: perspectives from healthcare providers in Georgia. Published in the journal AIDS Care.

Development of the Motivational Interviewing Coach Rating Scale (MI-CRS) for health equity implementation contexts. Published in the journal Health Psychology.

Scaling Up CareKit: Lessons Learned from Expansion of a Centralized Home HIV and Sexually Transmitted Infection Testing Program. Published in the journal Sexually Transmitted Diseases.

Adolescents may accurately self-collect pharyngeal and rectal clinical specimens for the detection of Chlamydia trachomatis and Neisseria Gonorrhoeae infection. Published in the journal PLOS One.

Influence of dapivirine vaginal ring use on cervicovaginal immunity and functional microbiome in adolescent girls. Published in the journal AIDS.

Funding Opportunities

Advancing HIV/AIDS Research at the Intersection of Oral and Mental Health (R21 Clinical Trial Not Allowed)

The National Institutes of Health (NIH) Sexual & Gender Minority Research Office Request for Nominations for 2022 SGM Research Investigator Awards Program

Substance Abuse and HIV Prevention Navigator Program for Racial/Ethnic Minorities Cooperative Agreement, The Substance Abuse and Mental Health Services Administration (SAMHSA)

The full list of additional selected funding opportunities is here.

News

Clinical Trial for HIV Vaccines Launched

Three experimental mRNA vaccines will be studied in HVTN 302 and is funded by NIAID. See the news release from the NIH on the launch of the phase 1 clinical trial.

Findings on Digital Tool for Youth HIV Testing

Researchers measured the responses of youth in a New York City ER who were prompted to take an HIV test through a digital tool on a tablet device. Their responses on the mobile device were compared to responses by youth who were asked face-to-face. The study was funded partially by the NIH Eunice Kennedy Shriver National Institute of Child Health and Human Behavior (NICHD). Results from this study were announced this month - read the news release here.

NICHD - 60 Years of Innovation

See advances, milestones, and current strategic plans for NICHD, which was founded in 1962.

Also just announced - Read the news release on the appointment of Rohan Hazra, MD to the director of the NICHD Division of Extramural Research.

Guidance for COVID-19 and People with HIV

The guidance was updated in late February and is posted on HIV.gov. View the update here.

An Early Look at Baseline Data

ATN iTech published a new infographic with details about early baseline data for participants in the studies LYNX and MyChoices. View the iTech infographic here.

National Transgender HIV Testing Day

April 18 is National Transgender HIV Testing Day. See more from the Centers for Disease Control and Prevention (CDC) here.

Office of AIDS Research Advisory Council (OARAC) - February 2022

The NIH Office of AIDS Research met on February 24 with an agenda including the All of Us research program, clinical guideline updates, and discussion on HIV and COVID-19. See the recording here on the NIH website.

Overview of Health Disparities Report Released

An interactive report on health disparities over time was released this month from the National Center for Health Statistics (NCHS) for its Healthy People 2020 Final Review. View details here.

Conferences and Events

Below are featured events, and you can view the full list on the ATN website: Research meetings and conferences, for HIV prevention and care, youth-centered health, and major events for public health research.

Featured Events:

April 25, 2022: Early Career Investigators in HIV/AIDS Workshop. 12 - 4:30pm ET. From the National Institutes of Health Office of AIDS Research.

July 11-13, 2022: Adherence 2022. Washington, DC and hybrid online format.

July 29 - August 2, 2022. AIDS 2022. Montreal, Canada and virtually. Registration is open. See the list of featured speakers for the conference.

April 27-28, 2022: The Spring ATN Meeting. Virtual event.

About Your ATN Presentations / Abstracts ...

Are you part of the ATN and presenting at an upcoming event, or have recently had an abstract accepted to a conference? Please email atnhelp@unc.edu to let us know.

Tell Your Colleagues About the ATN Monthly Newsletter: The newsletter is open to the public and anyone can subscribe. Feel free to tell your colleagues about it and send them this link to subscribe: https://atnweb.org/atnweb/atn-newsletter

Adolescent Medicine Trials Network (ATN)

TO UNSUBSCRIBE: Email ccritz@email.unc.edu

Collaborative Studies Coordinating Center, Department of Biostatistics, University of North Carolina's Gillings School of Global Public Health. 123 W. Franklin St., Suite 450, Chapel Hill, NC 27516

https://sph.unc.edu/